Sarafem
Sarafem Brand names, Sarafem Analogs
Sarafem Brand Names Mixture
- No information avaliable
Sarafem Chemical_Formula
C17H18F3NO
Sarafem RX_link
http://www.rxlist.com/cgi/generic/fluoxetine.htm
Sarafem fda sheet
Sarafem msds (material safety sheet)
Sarafem Synthesis Reference
B. B. Mally; K. K. Schmiegel; U.S. Pat. 4,314,081 (1982)
Sarafem Molecular Weight
309.326 g/mol
Sarafem Melting Point
179-182oC
Sarafem H2O Solubility
50 mg/mL at 25°C
Sarafem State
Solid
Sarafem LogP
5.37
Sarafem Dosage Forms
Capsule; Liquid; Solution
Sarafem Indication
For the treatment of depression, obsessive compulsive disorder, and bulimia nervosa.
Sarafem Pharmacology
Fluoxetine, an antidepressant agent belonging to the selective serotonin reuptake inhibitors (SSRIs), is used to treat depression, bulimia nervosa, premenstrual dysphoric disorder, panic disorder and post-traumatic stress. According to the amines hypothesis, a functional decrease in the activity of amines, such as serotonin and norepinephrine, would result in depression; a functional increase of the activity of these amines would result in mood elevation. Fluoxetine's effects are thought to be associated with the inhibition of 5HT receptor, which leads to an increase of serotonin level.
Sarafem Absorption
72%
Sarafem side effects and Toxicity
Symptoms of overdose include agitation, restlessness, hypomania, and other signs of CNS excitation. LD50=284mg/kg (orally in mice).
Sarafem Patient Information
Sarafem Organisms Affected
Humans and other mammals
