Fluoxetine Hydrochloride
Fluoxetine Hydrochloride Brand names, Fluoxetine Hydrochloride Analogs
Fluoxetine Hydrochloride Brand Names Mixture
- No information avaliable
Fluoxetine Hydrochloride Chemical_Formula
C17H18F3NO
Fluoxetine Hydrochloride RX_link
http://www.rxlist.com/cgi/generic/fluoxetine.htm
Fluoxetine Hydrochloride fda sheet
Fluoxetine Hydrochloride msds (material safety sheet)
Fluoxetine Hydrochloride Synthesis Reference
B. B. Mally; K. K. Schmiegel; U.S. Pat. 4,314,081 (1982)
Fluoxetine Hydrochloride Molecular Weight
309.326 g/mol
Fluoxetine Hydrochloride Melting Point
179-182oC
Fluoxetine Hydrochloride H2O Solubility
50 mg/mL at 25°C
Fluoxetine Hydrochloride State
Solid
Fluoxetine Hydrochloride LogP
5.37
Fluoxetine Hydrochloride Dosage Forms
Capsule; Liquid; Solution
Fluoxetine Hydrochloride Indication
For the treatment of depression, obsessive compulsive disorder, and bulimia nervosa.
Fluoxetine Hydrochloride Pharmacology
Fluoxetine, an antidepressant agent belonging to the selective serotonin reuptake inhibitors (SSRIs), is used to treat depression, bulimia nervosa, premenstrual dysphoric disorder, panic disorder and post-traumatic stress. According to the amines hypothesis, a functional decrease in the activity of amines, such as serotonin and norepinephrine, would result in depression; a functional increase of the activity of these amines would result in mood elevation. Fluoxetine's effects are thought to be associated with the inhibition of 5HT receptor, which leads to an increase of serotonin level.
Fluoxetine Hydrochloride Absorption
72%
Fluoxetine Hydrochloride side effects and Toxicity
Symptoms of overdose include agitation, restlessness, hypomania, and other signs of CNS excitation. LD50=284mg/kg (orally in mice).
Fluoxetine Hydrochloride Patient Information
Fluoxetine Hydrochloride Organisms Affected
Humans and other mammals
