Deprex
Brand names,
Deprex
Analogs
Deprex
Brand Names Mixture
Deprex
Chemical_Formula
C17H18F3NO
Deprex
RX_link
http://www.rxlist.com/cgi/generic/fluoxetine.htm
Deprex
fda sheet
Deprex
msds (material safety sheet)
Deprex
Synthesis Reference
B. B. Mally; K. K. Schmiegel; U.S. Pat. 4,314,081 (1982)
Deprex
Molecular Weight
309.326 g/mol
Deprex
Melting Point
179-182oC
Deprex
H2O Solubility
50 mg/mL at 25°C
Deprex
State
Solid
Deprex
LogP
5.37
Deprex
Dosage Forms
Capsule; Liquid; Solution
Deprex
Indication
For the treatment of depression, obsessive compulsive disorder, and bulimia nervosa.
Deprex
Pharmacology
Fluoxetine, an antidepressant agent belonging to the selective serotonin reuptake inhibitors (SSRIs), is used to treat depression, bulimia nervosa, premenstrual dysphoric disorder, panic disorder and post-traumatic stress. According to the amines hypothesis, a functional decrease in the activity of amines, such as serotonin and norepinephrine, would result in depression; a functional increase of the activity of these amines would result in mood elevation. Fluoxetine's effects are thought to be associated with the inhibition of 5HT receptor, which leads to an increase of serotonin level.
Deprex
Absorption
72%
Deprex
side effects and Toxicity
Symptoms of overdose include agitation, restlessness, hypomania, and other signs of CNS excitation. LD50=284mg/kg (orally in mice).
Deprex
Patient Information
Deprex
Organisms Affected
Humans and other mammals