Portal
Portal Brand names, Portal Analogs
Portal Brand Names Mixture
- No information avaliable
Portal Chemical_Formula
C17H18F3NO
Portal RX_link
http://www.rxlist.com/cgi/generic/fluoxetine.htm
Portal fda sheet
Portal msds (material safety sheet)
Portal Synthesis Reference
B. B. Mally; K. K. Schmiegel; U.S. Pat. 4,314,081 (1982)
Portal Molecular Weight
309.326 g/mol
Portal Melting Point
179-182oC
Portal H2O Solubility
50 mg/mL at 25°C
Portal State
Solid
Portal LogP
5.37
Portal Dosage Forms
Capsule; Liquid; Solution
Portal Indication
For the treatment of depression, obsessive compulsive disorder, and bulimia nervosa.
Portal Pharmacology
Fluoxetine, an antidepressant agent belonging to the selective serotonin reuptake inhibitors (SSRIs), is used to treat depression, bulimia nervosa, premenstrual dysphoric disorder, panic disorder and post-traumatic stress. According to the amines hypothesis, a functional decrease in the activity of amines, such as serotonin and norepinephrine, would result in depression; a functional increase of the activity of these amines would result in mood elevation. Fluoxetine's effects are thought to be associated with the inhibition of 5HT receptor, which leads to an increase of serotonin level.
Portal Absorption
72%
Portal side effects and Toxicity
Symptoms of overdose include agitation, restlessness, hypomania, and other signs of CNS excitation. LD50=284mg/kg (orally in mice).
Portal Patient Information
Portal Organisms Affected
Humans and other mammals
