Reneuron
Brand names,
Reneuron
Analogs
Reneuron
Brand Names Mixture
Reneuron
Chemical_Formula
C17H18F3NO
Reneuron
RX_link
http://www.rxlist.com/cgi/generic/fluoxetine.htm
Reneuron
fda sheet
Reneuron
msds (material safety sheet)
Reneuron
Synthesis Reference
B. B. Mally; K. K. Schmiegel; U.S. Pat. 4,314,081 (1982)
Reneuron
Molecular Weight
309.326 g/mol
Reneuron
Melting Point
179-182oC
Reneuron
H2O Solubility
50 mg/mL at 25°C
Reneuron
State
Solid
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LogP
5.37
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Dosage Forms
Capsule; Liquid; Solution
Reneuron
Indication
For the treatment of depression, obsessive compulsive disorder, and bulimia nervosa.
Reneuron
Pharmacology
Fluoxetine, an antidepressant agent belonging to the selective serotonin reuptake inhibitors (SSRIs), is used to treat depression, bulimia nervosa, premenstrual dysphoric disorder, panic disorder and post-traumatic stress. According to the amines hypothesis, a functional decrease in the activity of amines, such as serotonin and norepinephrine, would result in depression; a functional increase of the activity of these amines would result in mood elevation. Fluoxetine's effects are thought to be associated with the inhibition of 5HT receptor, which leads to an increase of serotonin level.
Reneuron
Absorption
72%
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side effects and Toxicity
Symptoms of overdose include agitation, restlessness, hypomania, and other signs of CNS excitation. LD50=284mg/kg (orally in mice).
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Patient Information
Reneuron
Organisms Affected
Humans and other mammals