Pyridoxine HCl en es it fr

Pyridoxine HCl Brand names, Pyridoxine HCl Analogs

Pyridoxine HCl Brand Names Mixture

  • No information avaliable

Pyridoxine HCl Chemical_Formula


Pyridoxine HCl RX_link

No information avaliable

Pyridoxine HCl fda sheet

Pyridoxine HCl msds (material safety sheet)

Pyridoxine_HCl MSDS

Pyridoxine HCl Synthesis Reference

No information avaliable

Pyridoxine HCl Molecular Weight

169.178 g/mol

Pyridoxine HCl Melting Point

207 oC

Pyridoxine HCl H2O Solubility

2.2E+005 mg/L

Pyridoxine HCl State


Pyridoxine HCl LogP


Pyridoxine HCl Dosage Forms


Pyridoxine HCl Indication

For the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy.

Pyridoxine HCl Pharmacology

Vitamin B6 (pyridoxine) is a water-soluble vitamin used in the prophylaxis and treatment of vitamin B6 deficiency and peripheral neuropathy in those receiving isoniazid (isonicotinic acid hydrazide, INH). Vitamin B6 has been found to lower systolic and diastolic blood pressure in a small group of subjects with essential hypertension. Hypertension is another risk factor for atherosclerosis and coronary heart disease. Another study showed pyridoxine hydrochloride to inhibit ADP- or epinephrine-induced platelet aggregation and to lower total cholesterol levels and increase HDL-cholesterol levels, again in a small group of subjects. Vitamin B6, in the form of pyridoxal 5'-phosphate, was found to protect vascular endothelial cells in culture from injury by activated platelets. Endothelial injury and dysfunction are critical initiating events in the pathogenesis of atherosclerosis. Human studies have demonstrated that vitamin B6 deficiency affects cellular and humoral responses of the immune system. Vitamin B6 deficiency results in altered lymphocyte differentiation and maturation, reduced delayed-type hypersensitivity (DTH) responses, impaired antibody production, decreased lymphocyte proliferation and decreased interleukin (IL)-2 production, among other immunologic activities.

Pyridoxine HCl Absorption

Readily absorbed

Pyridoxine HCl side effects and Toxicity

Oral Rat LD50 = 4 gm/kg. Toxic effects include convulsions, dyspnea, hypermotility, diarrhea, ataxia and muscle weakness.

Pyridoxine HCl Patient Information

No information avaliable

Pyridoxine HCl Organisms Affected

Humans and other mammals