Nestrex
Nestrex Brand names, Nestrex Analogs
- Adermin hydrochloride
- Adermine hydrochloride
- Aderomine hydrochloride
- Aderoxine
- Alestrol
- Becilan
- Beesix
- Benadon
- Bonasanit
- Campoviton 6
- Gravidox
- Hexa-Betalin
- Hexabione hydrochloride
- Hexavibex
- Hexermin
- Hexermine
- Hexobion
- Hydoxin
- Nestrex
- Pydox
- Pyridipca
- Pyridox
- Pyridoxal
- Pyridoxamine
- Pyridoxin hydrochloride
- Pyridoxine Chloride
- Pyridoxine HCl
- Pyridoxine hydrochloride
- Pyridoxine hydrogen chloride
- Pyridoxine-HCl Microencapsulated
- Pyridoxinium Chloride
- Pyridoxinum Hydrochloricum
- Pyridoxol hydrochloride
- Rodex TD
- Tex Six T.R.
- Vitamin B
- Vitamin B6 hydrochloride
Nestrex Brand Names Mixture
- No information avaliable
Nestrex Chemical_Formula
C8H11NO3
Nestrex RX_link
No information avaliable
Nestrex fda sheet
Nestrex msds (material safety sheet)
Nestrex Synthesis Reference
No information avaliable
Nestrex Molecular Weight
169.178 g/mol
Nestrex Melting Point
207 oC
Nestrex H2O Solubility
2.2E+005 mg/L
Nestrex State
Solid
Nestrex LogP
-0.784
Nestrex Dosage Forms
Capsules
Nestrex Indication
For the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy.
Nestrex Pharmacology
Vitamin B6 (pyridoxine) is a water-soluble vitamin used in the prophylaxis and treatment of vitamin B6 deficiency and peripheral neuropathy in those receiving isoniazid (isonicotinic acid hydrazide, INH). Vitamin B6 has been found to lower systolic and diastolic blood pressure in a small group of subjects with essential hypertension. Hypertension is another risk factor for atherosclerosis and coronary heart disease. Another study showed pyridoxine hydrochloride to inhibit ADP- or epinephrine-induced platelet aggregation and to lower total cholesterol levels and increase HDL-cholesterol levels, again in a small group of subjects. Vitamin B6, in the form of pyridoxal 5'-phosphate, was found to protect vascular endothelial cells in culture from injury by activated platelets. Endothelial injury and dysfunction are critical initiating events in the pathogenesis of atherosclerosis. Human studies have demonstrated that vitamin B6 deficiency affects cellular and humoral responses of the immune system. Vitamin B6 deficiency results in altered lymphocyte differentiation and maturation, reduced delayed-type hypersensitivity (DTH) responses, impaired antibody production, decreased lymphocyte proliferation and decreased interleukin (IL)-2 production, among other immunologic activities.
Nestrex Absorption
Readily absorbed
Nestrex side effects and Toxicity
Oral Rat LD50 = 4 gm/kg. Toxic effects include convulsions, dyspnea, hypermotility, diarrhea, ataxia and muscle weakness.
Nestrex Patient Information
No information avaliable
Nestrex Organisms Affected
Humans and other mammals
