Pyridoxine-HCl Microencapsulated en es it fr

Pyridoxine-HCl Microencapsulated Brand names, Pyridoxine-HCl Microencapsulated Analogs

Pyridoxine-HCl Microencapsulated Brand Names Mixture

  • No information avaliable

Pyridoxine-HCl Microencapsulated Chemical_Formula

C8H11NO3

Pyridoxine-HCl Microencapsulated RX_link

No information avaliable

Pyridoxine-HCl Microencapsulated fda sheet

Pyridoxine-HCl Microencapsulated msds (material safety sheet)

Pyridoxine-HCl_Microencapsulated MSDS

Pyridoxine-HCl Microencapsulated Synthesis Reference

No information avaliable

Pyridoxine-HCl Microencapsulated Molecular Weight

169.178 g/mol

Pyridoxine-HCl Microencapsulated Melting Point

207 oC

Pyridoxine-HCl Microencapsulated H2O Solubility

2.2E+005 mg/L

Pyridoxine-HCl Microencapsulated State

Solid

Pyridoxine-HCl Microencapsulated LogP

-0.784

Pyridoxine-HCl Microencapsulated Dosage Forms

Capsules

Pyridoxine-HCl Microencapsulated Indication

For the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy.

Pyridoxine-HCl Microencapsulated Pharmacology

Vitamin B6 (pyridoxine) is a water-soluble vitamin used in the prophylaxis and treatment of vitamin B6 deficiency and peripheral neuropathy in those receiving isoniazid (isonicotinic acid hydrazide, INH). Vitamin B6 has been found to lower systolic and diastolic blood pressure in a small group of subjects with essential hypertension. Hypertension is another risk factor for atherosclerosis and coronary heart disease. Another study showed pyridoxine hydrochloride to inhibit ADP- or epinephrine-induced platelet aggregation and to lower total cholesterol levels and increase HDL-cholesterol levels, again in a small group of subjects. Vitamin B6, in the form of pyridoxal 5'-phosphate, was found to protect vascular endothelial cells in culture from injury by activated platelets. Endothelial injury and dysfunction are critical initiating events in the pathogenesis of atherosclerosis. Human studies have demonstrated that vitamin B6 deficiency affects cellular and humoral responses of the immune system. Vitamin B6 deficiency results in altered lymphocyte differentiation and maturation, reduced delayed-type hypersensitivity (DTH) responses, impaired antibody production, decreased lymphocyte proliferation and decreased interleukin (IL)-2 production, among other immunologic activities.

Pyridoxine-HCl Microencapsulated Absorption

Readily absorbed

Pyridoxine-HCl Microencapsulated side effects and Toxicity

Oral Rat LD50 = 4 gm/kg. Toxic effects include convulsions, dyspnea, hypermotility, diarrhea, ataxia and muscle weakness.

Pyridoxine-HCl Microencapsulated Patient Information

No information avaliable

Pyridoxine-HCl Microencapsulated Organisms Affected

Humans and other mammals