Phentermine
Brand names,
Phentermine
Analogs
Phentermine
Brand Names Mixture
Phentermine
Chemical_Formula
C10H15N
Phentermine
RX_link
http://www.rxlist.com/cgi/generic/phenterm.htm
Phentermine
fda sheet
Phentermine
msds (material safety sheet)
Phentermine
Synthesis Reference
No information avaliable
Phentermine
Molecular Weight
149.233 g/mol
Phentermine
Melting Point
205 oC
Phentermine
H2O Solubility
18.6 g/L
Phentermine
State
Solid
Phentermine
LogP
2.194
Phentermine
Dosage Forms
Capsule (30 mg)
Phentermine
Indication
For the treatment and management of obesity.
Phentermine
Pharmacology
Phentermine is indicated in the management of exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction. Phentermine hydrochloride is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for.
Phentermine
Absorption
Phentermine is rapidly absorbed after oral ingestion.
Phentermine
side effects and Toxicity
LD50 is adult monkeys is 15 to 20 mg/kg. Symptoms of overdose include delirium, mania, self-injury, marked hypertension, tachycardia, arrhythmia, hyperpyrexia, convulsion, coma, and circulatory collapse.
Phentermine
Patient Information
No information avaliable
Phentermine
Organisms Affected
Humans and other mammals