Oby-Trim
Brand names,
Oby-Trim
Analogs
Oby-Trim
Brand Names Mixture
Oby-Trim
Chemical_Formula
C10H15N
Oby-Trim
RX_link
http://www.rxlist.com/cgi/generic/phenterm.htm
Oby-Trim
fda sheet
Oby-Trim
msds (material safety sheet)
Oby-Trim
Synthesis Reference
No information avaliable
Oby-Trim
Molecular Weight
149.233 g/mol
Oby-Trim
Melting Point
205 oC
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H2O Solubility
18.6 g/L
Oby-Trim
State
Solid
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LogP
2.194
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Dosage Forms
Capsule (30 mg)
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Indication
For the treatment and management of obesity.
Oby-Trim
Pharmacology
Phentermine is indicated in the management of exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction. Phentermine hydrochloride is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for.
Oby-Trim
Absorption
Phentermine is rapidly absorbed after oral ingestion.
Oby-Trim
side effects and Toxicity
LD50 is adult monkeys is 15 to 20 mg/kg. Symptoms of overdose include delirium, mania, self-injury, marked hypertension, tachycardia, arrhythmia, hyperpyrexia, convulsion, coma, and circulatory collapse.
Oby-Trim
Patient Information
No information avaliable
Oby-Trim
Organisms Affected
Humans and other mammals