Phentermine Hydrochloride
Brand names,
Phentermine Hydrochloride
Analogs
Phentermine Hydrochloride
Brand Names Mixture
Phentermine Hydrochloride
Chemical_Formula
C10H15N
Phentermine Hydrochloride
RX_link
http://www.rxlist.com/cgi/generic/phenterm.htm
Phentermine Hydrochloride
fda sheet
Phentermine Hydrochloride
msds (material safety sheet)
Phentermine Hydrochloride
Synthesis Reference
No information avaliable
Phentermine Hydrochloride
Molecular Weight
149.233 g/mol
Phentermine Hydrochloride
Melting Point
205 oC
Phentermine Hydrochloride
H2O Solubility
18.6 g/L
Phentermine Hydrochloride
State
Solid
Phentermine Hydrochloride
LogP
2.194
Phentermine Hydrochloride
Dosage Forms
Capsule (30 mg)
Phentermine Hydrochloride
Indication
For the treatment and management of obesity.
Phentermine Hydrochloride
Pharmacology
Phentermine is indicated in the management of exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction. Phentermine hydrochloride is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for.
Phentermine Hydrochloride
Absorption
Phentermine is rapidly absorbed after oral ingestion.
Phentermine Hydrochloride
side effects and Toxicity
LD50 is adult monkeys is 15 to 20 mg/kg. Symptoms of overdose include delirium, mania, self-injury, marked hypertension, tachycardia, arrhythmia, hyperpyrexia, convulsion, coma, and circulatory collapse.
Phentermine Hydrochloride
Patient Information
No information avaliable
Phentermine Hydrochloride
Organisms Affected
Humans and other mammals