Wilpo
Brand names,
Wilpo
Analogs
Wilpo
Brand Names Mixture
Wilpo
Chemical_Formula
C10H15N
Wilpo
RX_link
http://www.rxlist.com/cgi/generic/phenterm.htm
Wilpo
fda sheet
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msds (material safety sheet)
Wilpo
Synthesis Reference
No information avaliable
Wilpo
Molecular Weight
149.233 g/mol
Wilpo
Melting Point
205 oC
Wilpo
H2O Solubility
18.6 g/L
Wilpo
State
Solid
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LogP
2.194
Wilpo
Dosage Forms
Capsule (30 mg)
Wilpo
Indication
For the treatment and management of obesity.
Wilpo
Pharmacology
Phentermine is indicated in the management of exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction. Phentermine hydrochloride is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for.
Wilpo
Absorption
Phentermine is rapidly absorbed after oral ingestion.
Wilpo
side effects and Toxicity
LD50 is adult monkeys is 15 to 20 mg/kg. Symptoms of overdose include delirium, mania, self-injury, marked hypertension, tachycardia, arrhythmia, hyperpyrexia, convulsion, coma, and circulatory collapse.
Wilpo
Patient Information
No information avaliable
Wilpo
Organisms Affected
Humans and other mammals