Duromine
Brand names,
Duromine
Analogs
Duromine
Brand Names Mixture
Duromine
Chemical_Formula
C10H15N
Duromine
RX_link
http://www.rxlist.com/cgi/generic/phenterm.htm
Duromine
fda sheet
Duromine
msds (material safety sheet)
Duromine
Synthesis Reference
No information avaliable
Duromine
Molecular Weight
149.233 g/mol
Duromine
Melting Point
205 oC
Duromine
H2O Solubility
18.6 g/L
Duromine
State
Solid
Duromine
LogP
2.194
Duromine
Dosage Forms
Capsule (30 mg)
Duromine
Indication
For the treatment and management of obesity.
Duromine
Pharmacology
Phentermine is indicated in the management of exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction. Phentermine hydrochloride is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for.
Duromine
Absorption
Phentermine is rapidly absorbed after oral ingestion.
Duromine
side effects and Toxicity
LD50 is adult monkeys is 15 to 20 mg/kg. Symptoms of overdose include delirium, mania, self-injury, marked hypertension, tachycardia, arrhythmia, hyperpyrexia, convulsion, coma, and circulatory collapse.
Duromine
Patient Information
No information avaliable
Duromine
Organisms Affected
Humans and other mammals