Phentride
Brand names,
Phentride
Analogs
Phentride
Brand Names Mixture
Phentride
Chemical_Formula
C10H15N
Phentride
RX_link
http://www.rxlist.com/cgi/generic/phenterm.htm
Phentride
fda sheet
Phentride
msds (material safety sheet)
Phentride
Synthesis Reference
No information avaliable
Phentride
Molecular Weight
149.233 g/mol
Phentride
Melting Point
205 oC
Phentride
H2O Solubility
18.6 g/L
Phentride
State
Solid
Phentride
LogP
2.194
Phentride
Dosage Forms
Capsule (30 mg)
Phentride
Indication
For the treatment and management of obesity.
Phentride
Pharmacology
Phentermine is indicated in the management of exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction. Phentermine hydrochloride is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for.
Phentride
Absorption
Phentermine is rapidly absorbed after oral ingestion.
Phentride
side effects and Toxicity
LD50 is adult monkeys is 15 to 20 mg/kg. Symptoms of overdose include delirium, mania, self-injury, marked hypertension, tachycardia, arrhythmia, hyperpyrexia, convulsion, coma, and circulatory collapse.
Phentride
Patient Information
No information avaliable
Phentride
Organisms Affected
Humans and other mammals