(alpha,alpha)-Dimethylphenethylamine
Brand names,
(alpha,alpha)-Dimethylphenethylamine
Analogs
(alpha,alpha)-Dimethylphenethylamine
Brand Names Mixture
(alpha,alpha)-Dimethylphenethylamine
Chemical_Formula
C10H15N
(alpha,alpha)-Dimethylphenethylamine
RX_link
http://www.rxlist.com/cgi/generic/phenterm.htm
(alpha,alpha)-Dimethylphenethylamine
fda sheet
(alpha,alpha)-Dimethylphenethylamine
msds (material safety sheet)
(alpha,alpha)-Dimethylphenethylamine
Synthesis Reference
No information avaliable
(alpha,alpha)-Dimethylphenethylamine
Molecular Weight
149.233 g/mol
(alpha,alpha)-Dimethylphenethylamine
Melting Point
205 oC
(alpha,alpha)-Dimethylphenethylamine
H2O Solubility
18.6 g/L
(alpha,alpha)-Dimethylphenethylamine
State
Solid
(alpha,alpha)-Dimethylphenethylamine
LogP
2.194
(alpha,alpha)-Dimethylphenethylamine
Dosage Forms
Capsule (30 mg)
(alpha,alpha)-Dimethylphenethylamine
Indication
For the treatment and management of obesity.
(alpha,alpha)-Dimethylphenethylamine
Pharmacology
Phentermine is indicated in the management of exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction. Phentermine hydrochloride is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for.
(alpha,alpha)-Dimethylphenethylamine
Absorption
Phentermine is rapidly absorbed after oral ingestion.
(alpha,alpha)-Dimethylphenethylamine
side effects and Toxicity
LD50 is adult monkeys is 15 to 20 mg/kg. Symptoms of overdose include delirium, mania, self-injury, marked hypertension, tachycardia, arrhythmia, hyperpyrexia, convulsion, coma, and circulatory collapse.
(alpha,alpha)-Dimethylphenethylamine
Patient Information
No information avaliable
(alpha,alpha)-Dimethylphenethylamine
Organisms Affected
Humans and other mammals