Nemurel
Nemurel Brand names, Nemurel Analogs
Nemurel Brand Names Mixture
- No information avaliable
Nemurel Chemical_Formula
C8H10N2S
Nemurel RX_link
http://www.rxlist.com/cgi/generic2/ethionamide.htm
Nemurel fda sheet
Nemurel msds (material safety sheet)
Nemurel Synthesis Reference
No information avaliable
Nemurel Molecular Weight
166.244 g/mol
Nemurel Melting Point
163 oC
Nemurel H2O Solubility
Practically insoluble
Nemurel State
Solid
Nemurel LogP
0.705
Nemurel Dosage Forms
Tablet (250 mg)
Nemurel Indication
For use in the treatment of pulmonary and extrapulmonary tuberculosis when other antitubercular drugs have failed.
Nemurel Pharmacology
Ethinamate is bacteriostatic against M. tuberculosis. In a study examining ethionamide resistance, ethionamide administered orally initially decreased the number of culturable Mycobacterium tuberculosis organisms from the lungs of H37Rv infected mice. Drug resistance developed with continued ethionamide monotherapy, but did not occur when mice received ethionamide in combination with streptomycin or isoniazid.
Nemurel Absorption
Essentially completely absorbed following oral administration and not subjected to any appreciable first pass metabolism. Bioavailability approximately 100%.
Nemurel side effects and Toxicity
Symptoms of overdose include convulsions, nausea, and vomiting.
Nemurel Patient Information
No information avaliable
Nemurel Organisms Affected
Mycobacteria
