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Julodin Brand names, Julodin Analogs

Julodin Brand Names Mixture

  • No information avaliable

Julodin Chemical_Formula

C8H10N2S

Julodin RX_link

http://www.rxlist.com/cgi/generic2/ethionamide.htm

Julodin fda sheet

Julodin FDA

Julodin msds (material safety sheet)

Julodin MSDS

Julodin Synthesis Reference

No information avaliable

Julodin Molecular Weight

166.244 g/mol

Julodin Melting Point

163 oC

Julodin H2O Solubility

Practically insoluble

Julodin State

Solid

Julodin LogP

0.705

Julodin Dosage Forms

Tablet (250 mg)

Julodin Indication

For use in the treatment of pulmonary and extrapulmonary tuberculosis when other antitubercular drugs have failed.

Julodin Pharmacology

Ethinamate is bacteriostatic against M. tuberculosis. In a study examining ethionamide resistance, ethionamide administered orally initially decreased the number of culturable Mycobacterium tuberculosis organisms from the lungs of H37Rv infected mice. Drug resistance developed with continued ethionamide monotherapy, but did not occur when mice received ethionamide in combination with streptomycin or isoniazid.

Julodin Absorption

Essentially completely absorbed following oral administration and not subjected to any appreciable first pass metabolism. Bioavailability approximately 100%.

Julodin side effects and Toxicity

Symptoms of overdose include convulsions, nausea, and vomiting.

Julodin Patient Information

No information avaliable

Julodin Organisms Affected

Mycobacteria