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Esilgan Brand names, Esilgan Analogs

Esilgan Brand Names Mixture

  • No information avaliable

Esilgan Chemical_Formula

C8H10N2S

Esilgan RX_link

http://www.rxlist.com/cgi/generic2/ethionamide.htm

Esilgan fda sheet

Esilgan FDA

Esilgan msds (material safety sheet)

Esilgan MSDS

Esilgan Synthesis Reference

No information avaliable

Esilgan Molecular Weight

166.244 g/mol

Esilgan Melting Point

163 oC

Esilgan H2O Solubility

Practically insoluble

Esilgan State

Solid

Esilgan LogP

0.705

Esilgan Dosage Forms

Tablet (250 mg)

Esilgan Indication

For use in the treatment of pulmonary and extrapulmonary tuberculosis when other antitubercular drugs have failed.

Esilgan Pharmacology

Ethinamate is bacteriostatic against M. tuberculosis. In a study examining ethionamide resistance, ethionamide administered orally initially decreased the number of culturable Mycobacterium tuberculosis organisms from the lungs of H37Rv infected mice. Drug resistance developed with continued ethionamide monotherapy, but did not occur when mice received ethionamide in combination with streptomycin or isoniazid.

Esilgan Absorption

Essentially completely absorbed following oral administration and not subjected to any appreciable first pass metabolism. Bioavailability approximately 100%.

Esilgan side effects and Toxicity

Symptoms of overdose include convulsions, nausea, and vomiting.

Esilgan Patient Information

No information avaliable

Esilgan Organisms Affected

Mycobacteria