Eurodin
Eurodin Brand names, Eurodin Analogs
Eurodin Brand Names Mixture
- No information avaliable
Eurodin Chemical_Formula
C8H10N2S
Eurodin RX_link
http://www.rxlist.com/cgi/generic2/ethionamide.htm
Eurodin fda sheet
Eurodin msds (material safety sheet)
Eurodin Synthesis Reference
No information avaliable
Eurodin Molecular Weight
166.244 g/mol
Eurodin Melting Point
163 oC
Eurodin H2O Solubility
Practically insoluble
Eurodin State
Solid
Eurodin LogP
0.705
Eurodin Dosage Forms
Tablet (250 mg)
Eurodin Indication
For use in the treatment of pulmonary and extrapulmonary tuberculosis when other antitubercular drugs have failed.
Eurodin Pharmacology
Ethinamate is bacteriostatic against M. tuberculosis. In a study examining ethionamide resistance, ethionamide administered orally initially decreased the number of culturable Mycobacterium tuberculosis organisms from the lungs of H37Rv infected mice. Drug resistance developed with continued ethionamide monotherapy, but did not occur when mice received ethionamide in combination with streptomycin or isoniazid.
Eurodin Absorption
Essentially completely absorbed following oral administration and not subjected to any appreciable first pass metabolism. Bioavailability approximately 100%.
Eurodin side effects and Toxicity
Symptoms of overdose include convulsions, nausea, and vomiting.
Eurodin Patient Information
No information avaliable
Eurodin Organisms Affected
Mycobacteria
