Micafungin en es it fr

Micafungin Brand names, Micafungin Analogs

Micafungin Brand Names Mixture

  • No information avaliable

Micafungin Chemical_Formula


Micafungin RX_link


Micafungin fda sheet

Micafungin FDA

Micafungin msds (material safety sheet)

Micafungin MSDS

Micafungin Synthesis Reference

No information avaliable

Micafungin Molecular Weight

1270.28 g/mol

Micafungin Melting Point

No information avaliable

Micafungin H2O Solubility

Freely soluble as sodium salt (> 200mg/mL)

Micafungin State


Micafungin LogP

No information avaliable

Micafungin Dosage Forms

Powder for solution (for injection)

Micafungin Indication

For use in the treatment of patients with esophageal candidiasis and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.

Micafungin Pharmacology

Formerly known as FK463, micafungin is a novel antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. The U.S. Food and Drug Administration approved micafungin in March 2005. Micafungin inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Micafungin can be used concomitantly with a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus.

Micafungin Absorption

No information avaliable

Micafungin side effects and Toxicity

Intravenous LD50 in rats is 125mg/kg. In dogs it is >200mg/kg. No cases of overdosage have been reported. Repeated daily doses up to 8 mg/kg (maximum total dose of 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity. The minimum lethal dose is 125 mg/kg in rats, equivalent to 8.1 times the recommended human clinical dose for esophageal candidiasis based on body surface area comparisons.

Micafungin Patient Information

No information avaliable

Micafungin Organisms Affected

Aspergillis, Candida and other fungi