Aldoril D50 en es it fr

Aldoril D50 Brand names, Aldoril D50 Analogs

Aldoril D50 Brand Names Mixture

  • No information avaliable

Aldoril D50 Chemical_Formula


Aldoril D50 RX_link

Aldoril D50 fda sheet

Aldoril_D50 FDA

Aldoril D50 msds (material safety sheet)

Aldoril_D50 MSDS

Aldoril D50 Synthesis Reference

No information avaliable

Aldoril D50 Molecular Weight

1270.28 g/mol

Aldoril D50 Melting Point

No information avaliable

Aldoril D50 H2O Solubility

Freely soluble as sodium salt (> 200mg/mL)

Aldoril D50 State


Aldoril D50 LogP

No information avaliable

Aldoril D50 Dosage Forms

Powder for solution (for injection)

Aldoril D50 Indication

For use in the treatment of patients with esophageal candidiasis and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.

Aldoril D50 Pharmacology

Formerly known as FK463, micafungin is a novel antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. The U.S. Food and Drug Administration approved micafungin in March 2005. Micafungin inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Micafungin can be used concomitantly with a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus.

Aldoril D50 Absorption

No information avaliable

Aldoril D50 side effects and Toxicity

Intravenous LD50 in rats is 125mg/kg. In dogs it is >200mg/kg. No cases of overdosage have been reported. Repeated daily doses up to 8 mg/kg (maximum total dose of 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity. The minimum lethal dose is 125 mg/kg in rats, equivalent to 8.1 times the recommended human clinical dose for esophageal candidiasis based on body surface area comparisons.

Aldoril D50 Patient Information

No information avaliable

Aldoril D50 Organisms Affected

Aspergillis, Candida and other fungi