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AMD Brand names, AMD Analogs

AMD Brand Names Mixture

  • No information avaliable

AMD Chemical_Formula


AMD RX_link

AMD fda sheet


AMD msds (material safety sheet)


AMD Synthesis Reference

No information avaliable

AMD Molecular Weight

1270.28 g/mol

AMD Melting Point

No information avaliable

AMD H2O Solubility

Freely soluble as sodium salt (> 200mg/mL)

AMD State



No information avaliable

AMD Dosage Forms

Powder for solution (for injection)

AMD Indication

For use in the treatment of patients with esophageal candidiasis and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.

AMD Pharmacology

Formerly known as FK463, micafungin is a novel antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. The U.S. Food and Drug Administration approved micafungin in March 2005. Micafungin inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Micafungin can be used concomitantly with a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus.

AMD Absorption

No information avaliable

AMD side effects and Toxicity

Intravenous LD50 in rats is 125mg/kg. In dogs it is >200mg/kg. No cases of overdosage have been reported. Repeated daily doses up to 8 mg/kg (maximum total dose of 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity. The minimum lethal dose is 125 mg/kg in rats, equivalent to 8.1 times the recommended human clinical dose for esophageal candidiasis based on body surface area comparisons.

AMD Patient Information

No information avaliable

AMD Organisms Affected

Aspergillis, Candida and other fungi