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Becanta Brand names, Becanta Analogs

Becanta Brand Names Mixture

  • No information avaliable

Becanta Chemical_Formula

C56H71N9O23S

Becanta RX_link

http://www.rxlist.com/cgi/generic4/mycamine.htm

Becanta fda sheet

Becanta FDA

Becanta msds (material safety sheet)

Becanta MSDS

Becanta Synthesis Reference

No information avaliable

Becanta Molecular Weight

1270.28 g/mol

Becanta Melting Point

No information avaliable

Becanta H2O Solubility

Freely soluble as sodium salt (> 200mg/mL)

Becanta State

Solid

Becanta LogP

No information avaliable

Becanta Dosage Forms

Powder for solution (for injection)

Becanta Indication

For use in the treatment of patients with esophageal candidiasis and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.

Becanta Pharmacology

Formerly known as FK463, micafungin is a novel antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. The U.S. Food and Drug Administration approved micafungin in March 2005. Micafungin inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Micafungin can be used concomitantly with a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus.

Becanta Absorption

No information avaliable

Becanta side effects and Toxicity

Intravenous LD50 in rats is 125mg/kg. In dogs it is >200mg/kg. No cases of overdosage have been reported. Repeated daily doses up to 8 mg/kg (maximum total dose of 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity. The minimum lethal dose is 125 mg/kg in rats, equivalent to 8.1 times the recommended human clinical dose for esophageal candidiasis based on body surface area comparisons.

Becanta Patient Information

No information avaliable

Becanta Organisms Affected

Aspergillis, Candida and other fungi