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Sedometil Brand names, Sedometil Analogs

Sedometil Brand Names Mixture

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Sedometil Chemical_Formula


Sedometil RX_link

Sedometil fda sheet

Sedometil FDA

Sedometil msds (material safety sheet)

Sedometil MSDS

Sedometil Synthesis Reference

No information avaliable

Sedometil Molecular Weight

1270.28 g/mol

Sedometil Melting Point

No information avaliable

Sedometil H2O Solubility

Freely soluble as sodium salt (> 200mg/mL)

Sedometil State


Sedometil LogP

No information avaliable

Sedometil Dosage Forms

Powder for solution (for injection)

Sedometil Indication

For use in the treatment of patients with esophageal candidiasis and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.

Sedometil Pharmacology

Formerly known as FK463, micafungin is a novel antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. The U.S. Food and Drug Administration approved micafungin in March 2005. Micafungin inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Micafungin can be used concomitantly with a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus.

Sedometil Absorption

No information avaliable

Sedometil side effects and Toxicity

Intravenous LD50 in rats is 125mg/kg. In dogs it is >200mg/kg. No cases of overdosage have been reported. Repeated daily doses up to 8 mg/kg (maximum total dose of 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity. The minimum lethal dose is 125 mg/kg in rats, equivalent to 8.1 times the recommended human clinical dose for esophageal candidiasis based on body surface area comparisons.

Sedometil Patient Information

No information avaliable

Sedometil Organisms Affected

Aspergillis, Candida and other fungi