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Bayer 1440 L Brand names, Bayer 1440 L Analogs

Bayer 1440 L Brand Names Mixture

  • No information avaliable

Bayer 1440 L Chemical_Formula


Bayer 1440 L RX_link

Bayer 1440 L fda sheet

Bayer_1440_L FDA

Bayer 1440 L msds (material safety sheet)

Bayer_1440_L MSDS

Bayer 1440 L Synthesis Reference

No information avaliable

Bayer 1440 L Molecular Weight

1270.28 g/mol

Bayer 1440 L Melting Point

No information avaliable

Bayer 1440 L H2O Solubility

Freely soluble as sodium salt (> 200mg/mL)

Bayer 1440 L State


Bayer 1440 L LogP

No information avaliable

Bayer 1440 L Dosage Forms

Powder for solution (for injection)

Bayer 1440 L Indication

For use in the treatment of patients with esophageal candidiasis and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.

Bayer 1440 L Pharmacology

Formerly known as FK463, micafungin is a novel antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. The U.S. Food and Drug Administration approved micafungin in March 2005. Micafungin inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Micafungin can be used concomitantly with a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus.

Bayer 1440 L Absorption

No information avaliable

Bayer 1440 L side effects and Toxicity

Intravenous LD50 in rats is 125mg/kg. In dogs it is >200mg/kg. No cases of overdosage have been reported. Repeated daily doses up to 8 mg/kg (maximum total dose of 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity. The minimum lethal dose is 125 mg/kg in rats, equivalent to 8.1 times the recommended human clinical dose for esophageal candidiasis based on body surface area comparisons.

Bayer 1440 L Patient Information

No information avaliable

Bayer 1440 L Organisms Affected

Aspergillis, Candida and other fungi