Methyldopate HCL en es it fr

Methyldopate HCL Brand names, Methyldopate HCL Analogs

Methyldopate HCL Brand Names Mixture

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Methyldopate HCL Chemical_Formula


Methyldopate HCL RX_link

Methyldopate HCL fda sheet

Methyldopate_HCL FDA

Methyldopate HCL msds (material safety sheet)

Methyldopate_HCL MSDS

Methyldopate HCL Synthesis Reference

No information avaliable

Methyldopate HCL Molecular Weight

1270.28 g/mol

Methyldopate HCL Melting Point

No information avaliable

Methyldopate HCL H2O Solubility

Freely soluble as sodium salt (> 200mg/mL)

Methyldopate HCL State


Methyldopate HCL LogP

No information avaliable

Methyldopate HCL Dosage Forms

Powder for solution (for injection)

Methyldopate HCL Indication

For use in the treatment of patients with esophageal candidiasis and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.

Methyldopate HCL Pharmacology

Formerly known as FK463, micafungin is a novel antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. The U.S. Food and Drug Administration approved micafungin in March 2005. Micafungin inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Micafungin can be used concomitantly with a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus.

Methyldopate HCL Absorption

No information avaliable

Methyldopate HCL side effects and Toxicity

Intravenous LD50 in rats is 125mg/kg. In dogs it is >200mg/kg. No cases of overdosage have been reported. Repeated daily doses up to 8 mg/kg (maximum total dose of 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity. The minimum lethal dose is 125 mg/kg in rats, equivalent to 8.1 times the recommended human clinical dose for esophageal candidiasis based on body surface area comparisons.

Methyldopate HCL Patient Information

No information avaliable

Methyldopate HCL Organisms Affected

Aspergillis, Candida and other fungi