Melatonin
Melatonin Brand names, Melatonin Analogs
Melatonin Brand Names Mixture
- No information avaliable
Melatonin Chemical_Formula
C13H16N2O2
Melatonin RX_link
No information avaliable
Melatonin fda sheet
Melatonin msds (material safety sheet)
Melatonin Synthesis Reference
Szmuszkovicz et al., J. Org. Chem. 25, 857 (1960)
Melatonin Molecular Weight
232.278 g/mol
Melatonin Melting Point
117 oC
Melatonin H2O Solubility
No information avaliable
Melatonin State
Solid
Melatonin LogP
1.536
Melatonin Dosage Forms
Capsules; Liquid; Lozenge; Tablets
Melatonin Indication
For the treatment of insomnia and jet lag
Melatonin Pharmacology
Melatonin is a hormone normally produced in the pineal gland and released into the blood. The essential amino acid L-tryptophan is a precursor in the synthesis of melatonin. It helps regulate sleep-wake cycles or the circadian rhythm. Production of melatonin is stimulated by darkness and inhibited by light. High levels of melatonin induce sleep and so consumption of the drug can be used to combat insomnia and jet lag.
Melatonin Absorption
The absorption and bioavailability of melatonin varies widely.
Melatonin side effects and Toxicity
Oral, rat: LD50 = >3200 mg/kg
Melatonin Patient Information
Melatonin Organisms Affected
Humans and other mammals
