Melatol
Melatol Brand names, Melatol Analogs
Melatol Brand Names Mixture
- No information avaliable
Melatol Chemical_Formula
C13H16N2O2
Melatol RX_link
No information avaliable
Melatol fda sheet
Melatol msds (material safety sheet)
Melatol Synthesis Reference
Szmuszkovicz et al., J. Org. Chem. 25, 857 (1960)
Melatol Molecular Weight
232.278 g/mol
Melatol Melting Point
117 oC
Melatol H2O Solubility
No information avaliable
Melatol State
Solid
Melatol LogP
1.536
Melatol Dosage Forms
Capsules; Liquid; Lozenge; Tablets
Melatol Indication
For the treatment of insomnia and jet lag
Melatol Pharmacology
Melatonin is a hormone normally produced in the pineal gland and released into the blood. The essential amino acid L-tryptophan is a precursor in the synthesis of melatonin. It helps regulate sleep-wake cycles or the circadian rhythm. Production of melatonin is stimulated by darkness and inhibited by light. High levels of melatonin induce sleep and so consumption of the drug can be used to combat insomnia and jet lag.
Melatol Absorption
The absorption and bioavailability of melatonin varies widely.
Melatol side effects and Toxicity
Oral, rat: LD50 = >3200 mg/kg
Melatol Patient Information
Melatol Organisms Affected
Humans and other mammals
