Mela-T
Brand names,
Mela-T
Analogs
Mela-T
Brand Names Mixture
Mela-T
Chemical_Formula
C13H16N2O2
Mela-T
RX_link
No information avaliable
Mela-T
fda sheet
Mela-T
msds (material safety sheet)
Mela-T
Synthesis Reference
Szmuszkovicz et al., J. Org. Chem. 25, 857 (1960)
Mela-T
Molecular Weight
232.278 g/mol
Mela-T
Melting Point
117 oC
Mela-T
H2O Solubility
No information avaliable
Mela-T
State
Solid
Mela-T
LogP
1.536
Mela-T
Dosage Forms
Capsules; Liquid; Lozenge; Tablets
Mela-T
Indication
For the treatment of insomnia and jet lag
Mela-T
Pharmacology
Melatonin is a hormone normally produced in the pineal gland and released into the blood. The essential amino acid L-tryptophan is a precursor in the synthesis of melatonin. It helps regulate sleep-wake cycles or the circadian rhythm. Production of melatonin is stimulated by darkness and inhibited by light. High levels of melatonin induce sleep and so consumption of the drug can be used to combat insomnia and jet lag.
Mela-T
Absorption
The absorption and bioavailability of melatonin varies widely.
Mela-T
side effects and Toxicity
Oral, rat: LD50 = >3200 mg/kg
Mela-T
Patient Information
Mela-T
Organisms Affected
Humans and other mammals