Melatonex
Brand names,
Melatonex
Analogs
Melatonex
Brand Names Mixture
Melatonex
Chemical_Formula
C13H16N2O2
Melatonex
RX_link
No information avaliable
Melatonex
fda sheet
Melatonex
msds (material safety sheet)
Melatonex
Synthesis Reference
Szmuszkovicz et al., J. Org. Chem. 25, 857 (1960)
Melatonex
Molecular Weight
232.278 g/mol
Melatonex
Melting Point
117 oC
Melatonex
H2O Solubility
No information avaliable
Melatonex
State
Solid
Melatonex
LogP
1.536
Melatonex
Dosage Forms
Capsules; Liquid; Lozenge; Tablets
Melatonex
Indication
For the treatment of insomnia and jet lag
Melatonex
Pharmacology
Melatonin is a hormone normally produced in the pineal gland and released into the blood. The essential amino acid L-tryptophan is a precursor in the synthesis of melatonin. It helps regulate sleep-wake cycles or the circadian rhythm. Production of melatonin is stimulated by darkness and inhibited by light. High levels of melatonin induce sleep and so consumption of the drug can be used to combat insomnia and jet lag.
Melatonex
Absorption
The absorption and bioavailability of melatonin varies widely.
Melatonex
side effects and Toxicity
Oral, rat: LD50 = >3200 mg/kg
Melatonex
Patient Information
Melatonex
Organisms Affected
Humans and other mammals