Melatonine
Melatonine Brand names, Melatonine Analogs
Melatonine Brand Names Mixture
- No information avaliable
Melatonine Chemical_Formula
C13H16N2O2
Melatonine RX_link
No information avaliable
Melatonine fda sheet
Melatonine msds (material safety sheet)
Melatonine Synthesis Reference
Szmuszkovicz et al., J. Org. Chem. 25, 857 (1960)
Melatonine Molecular Weight
232.278 g/mol
Melatonine Melting Point
117 oC
Melatonine H2O Solubility
No information avaliable
Melatonine State
Solid
Melatonine LogP
1.536
Melatonine Dosage Forms
Capsules; Liquid; Lozenge; Tablets
Melatonine Indication
For the treatment of insomnia and jet lag
Melatonine Pharmacology
Melatonin is a hormone normally produced in the pineal gland and released into the blood. The essential amino acid L-tryptophan is a precursor in the synthesis of melatonin. It helps regulate sleep-wake cycles or the circadian rhythm. Production of melatonin is stimulated by darkness and inhibited by light. High levels of melatonin induce sleep and so consumption of the drug can be used to combat insomnia and jet lag.
Melatonine Absorption
The absorption and bioavailability of melatonin varies widely.
Melatonine side effects and Toxicity
Oral, rat: LD50 = >3200 mg/kg
Melatonine Patient Information
Melatonine Organisms Affected
Humans and other mammals
