Regulin
Brand names,
Regulin
Analogs
Regulin
Brand Names Mixture
Regulin
Chemical_Formula
C13H16N2O2
Regulin
RX_link
No information avaliable
Regulin
fda sheet
Regulin
msds (material safety sheet)
Regulin
Synthesis Reference
Szmuszkovicz et al., J. Org. Chem. 25, 857 (1960)
Regulin
Molecular Weight
232.278 g/mol
Regulin
Melting Point
117 oC
Regulin
H2O Solubility
No information avaliable
Regulin
State
Solid
Regulin
LogP
1.536
Regulin
Dosage Forms
Capsules; Liquid; Lozenge; Tablets
Regulin
Indication
For the treatment of insomnia and jet lag
Regulin
Pharmacology
Melatonin is a hormone normally produced in the pineal gland and released into the blood. The essential amino acid L-tryptophan is a precursor in the synthesis of melatonin. It helps regulate sleep-wake cycles or the circadian rhythm. Production of melatonin is stimulated by darkness and inhibited by light. High levels of melatonin induce sleep and so consumption of the drug can be used to combat insomnia and jet lag.
Regulin
Absorption
The absorption and bioavailability of melatonin varies widely.
Regulin
side effects and Toxicity
Oral, rat: LD50 = >3200 mg/kg
Regulin
Patient Information
Regulin
Organisms Affected
Humans and other mammals