Circadin
Circadin Brand names, Circadin Analogs
Circadin Brand Names Mixture
- No information avaliable
Circadin Chemical_Formula
C13H16N2O2
Circadin RX_link
No information avaliable
Circadin fda sheet
Circadin msds (material safety sheet)
Circadin Synthesis Reference
Szmuszkovicz et al., J. Org. Chem. 25, 857 (1960)
Circadin Molecular Weight
232.278 g/mol
Circadin Melting Point
117 oC
Circadin H2O Solubility
No information avaliable
Circadin State
Solid
Circadin LogP
1.536
Circadin Dosage Forms
Capsules; Liquid; Lozenge; Tablets
Circadin Indication
For the treatment of insomnia and jet lag
Circadin Pharmacology
Melatonin is a hormone normally produced in the pineal gland and released into the blood. The essential amino acid L-tryptophan is a precursor in the synthesis of melatonin. It helps regulate sleep-wake cycles or the circadian rhythm. Production of melatonin is stimulated by darkness and inhibited by light. High levels of melatonin induce sleep and so consumption of the drug can be used to combat insomnia and jet lag.
Circadin Absorption
The absorption and bioavailability of melatonin varies widely.
Circadin side effects and Toxicity
Oral, rat: LD50 = >3200 mg/kg
Circadin Patient Information
Circadin Organisms Affected
Humans and other mammals
