Melovine
Brand names,
Melovine
Analogs
Melovine
Brand Names Mixture
Melovine
Chemical_Formula
C13H16N2O2
Melovine
RX_link
No information avaliable
Melovine
fda sheet
Melovine
msds (material safety sheet)
Melovine
Synthesis Reference
Szmuszkovicz et al., J. Org. Chem. 25, 857 (1960)
Melovine
Molecular Weight
232.278 g/mol
Melovine
Melting Point
117 oC
Melovine
H2O Solubility
No information avaliable
Melovine
State
Solid
Melovine
LogP
1.536
Melovine
Dosage Forms
Capsules; Liquid; Lozenge; Tablets
Melovine
Indication
For the treatment of insomnia and jet lag
Melovine
Pharmacology
Melatonin is a hormone normally produced in the pineal gland and released into the blood. The essential amino acid L-tryptophan is a precursor in the synthesis of melatonin. It helps regulate sleep-wake cycles or the circadian rhythm. Production of melatonin is stimulated by darkness and inhibited by light. High levels of melatonin induce sleep and so consumption of the drug can be used to combat insomnia and jet lag.
Melovine
Absorption
The absorption and bioavailability of melatonin varies widely.
Melovine
side effects and Toxicity
Oral, rat: LD50 = >3200 mg/kg
Melovine
Patient Information
Melovine
Organisms Affected
Humans and other mammals