Mebendazole (JAN/USP) en es it fr

Mebendazole (JAN/USP) Brand names, Mebendazole (JAN/USP) Analogs

Mebendazole (JAN/USP) Brand Names Mixture

  • Absorbine JR Antifungal Liquid (menthol + tolnaftate)

Mebendazole (JAN/USP) Chemical_Formula

C9H18N2O4

Mebendazole (JAN/USP) RX_link

http://www.rxlist.com/cgi/generic2/meprobamate.htm

Mebendazole (JAN/USP) fda sheet

Mebendazole (JAN/USP) msds (material safety sheet)

Mebendazole_(JAN/USP) MSDS

Mebendazole (JAN/USP) Synthesis Reference

No information avaliable

Mebendazole (JAN/USP) Molecular Weight

218.25 g/mol

Mebendazole (JAN/USP) Melting Point

105 oC

Mebendazole (JAN/USP) H2O Solubility

4700 mg/L

Mebendazole (JAN/USP) State

Solid

Mebendazole (JAN/USP) LogP

0.092

Mebendazole (JAN/USP) Dosage Forms

Tablet for oral administration (200 mg, 400 mg)

Mebendazole (JAN/USP) Indication

For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety.

Mebendazole (JAN/USP) Pharmacology

Meprobamate is an anxiolytic drug. It was the best selling minor tranquilizer for a time but has largely been replaced by benzodiazepines. Meprobamate has most of the pharmacological effects and dangers of the barbiturates (though it was marketed as being safer). However, it is less sedating at effective doses. It is reported to have some anticonvulsant properties against absence seizures, but can exacerbate generalized tonic-clonic seizures. It has also been used as a hypnotic (sleeping pill). However, its is currently only licensed as an anxiolytic and it is a third or fourth-order choice.

Mebendazole (JAN/USP) Absorption

Well absorbed from the gastrointestinal tract.

Mebendazole (JAN/USP) side effects and Toxicity

Symptoms of overdose include coma, drowsiness, loss of muscle control, severely impaired breathing, shock, sluggishness, and unresponsiveness. Death has been reported with ingestion of as little as 12 g meprobamate and survival with as much as 40 g.

Mebendazole (JAN/USP) Patient Information

Mebendazole (JAN/USP) Organisms Affected

Humans and other mammals