MBDZ
Brand names,
MBDZ
Analogs
MBDZ
Brand Names Mixture
- Absorbine JR Antifungal Liquid (menthol + tolnaftate)
MBDZ
Chemical_Formula
C9H18N2O4
MBDZ
RX_link
http://www.rxlist.com/cgi/generic2/meprobamate.htm
MBDZ
fda sheet
MBDZ
msds (material safety sheet)
MBDZ
Synthesis Reference
No information avaliable
MBDZ
Molecular Weight
218.25 g/mol
MBDZ
Melting Point
105 oC
MBDZ
H2O Solubility
4700 mg/L
MBDZ
State
Solid
MBDZ
LogP
0.092
MBDZ
Dosage Forms
Tablet for oral administration (200 mg, 400 mg)
MBDZ
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety.
MBDZ
Pharmacology
Meprobamate is an anxiolytic drug. It was the best selling minor tranquilizer for a time but has largely been replaced by benzodiazepines. Meprobamate has most of the pharmacological effects and dangers of the barbiturates (though it was marketed as being safer). However, it is less sedating at effective doses. It is reported to have some anticonvulsant properties against absence seizures, but can exacerbate generalized tonic-clonic seizures. It has also been used as a hypnotic (sleeping pill). However, its is currently only licensed as an anxiolytic and it is a third or fourth-order choice.
MBDZ
Absorption
Well absorbed from the gastrointestinal tract.
MBDZ
side effects and Toxicity
Symptoms of overdose include coma, drowsiness, loss of muscle control, severely impaired breathing, shock, sluggishness, and unresponsiveness. Death has been reported with ingestion of as little as 12 g meprobamate and survival with as much as 40 g.
MBDZ
Patient Information
MBDZ
Organisms Affected
Humans and other mammals