Mebex
Brand names,
Mebex
Analogs
Mebex
Brand Names Mixture
- Absorbine JR Antifungal Liquid (menthol + tolnaftate)
Mebex
Chemical_Formula
C9H18N2O4
Mebex
RX_link
http://www.rxlist.com/cgi/generic2/meprobamate.htm
Mebex
fda sheet
Mebex
msds (material safety sheet)
Mebex
Synthesis Reference
No information avaliable
Mebex
Molecular Weight
218.25 g/mol
Mebex
Melting Point
105 oC
Mebex
H2O Solubility
4700 mg/L
Mebex
State
Solid
Mebex
LogP
0.092
Mebex
Dosage Forms
Tablet for oral administration (200 mg, 400 mg)
Mebex
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety.
Mebex
Pharmacology
Meprobamate is an anxiolytic drug. It was the best selling minor tranquilizer for a time but has largely been replaced by benzodiazepines. Meprobamate has most of the pharmacological effects and dangers of the barbiturates (though it was marketed as being safer). However, it is less sedating at effective doses. It is reported to have some anticonvulsant properties against absence seizures, but can exacerbate generalized tonic-clonic seizures. It has also been used as a hypnotic (sleeping pill). However, its is currently only licensed as an anxiolytic and it is a third or fourth-order choice.
Mebex
Absorption
Well absorbed from the gastrointestinal tract.
Mebex
side effects and Toxicity
Symptoms of overdose include coma, drowsiness, loss of muscle control, severely impaired breathing, shock, sluggishness, and unresponsiveness. Death has been reported with ingestion of as little as 12 g meprobamate and survival with as much as 40 g.
Mebex
Patient Information
Mebex
Organisms Affected
Humans and other mammals