Lomper
Brand names,
Lomper
Analogs
Lomper
Brand Names Mixture
- Absorbine JR Antifungal Liquid (menthol + tolnaftate)
Lomper
Chemical_Formula
C9H18N2O4
Lomper
RX_link
http://www.rxlist.com/cgi/generic2/meprobamate.htm
Lomper
fda sheet
Lomper
msds (material safety sheet)
Lomper
Synthesis Reference
No information avaliable
Lomper
Molecular Weight
218.25 g/mol
Lomper
Melting Point
105 oC
Lomper
H2O Solubility
4700 mg/L
Lomper
State
Solid
Lomper
LogP
0.092
Lomper
Dosage Forms
Tablet for oral administration (200 mg, 400 mg)
Lomper
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety.
Lomper
Pharmacology
Meprobamate is an anxiolytic drug. It was the best selling minor tranquilizer for a time but has largely been replaced by benzodiazepines. Meprobamate has most of the pharmacological effects and dangers of the barbiturates (though it was marketed as being safer). However, it is less sedating at effective doses. It is reported to have some anticonvulsant properties against absence seizures, but can exacerbate generalized tonic-clonic seizures. It has also been used as a hypnotic (sleeping pill). However, its is currently only licensed as an anxiolytic and it is a third or fourth-order choice.
Lomper
Absorption
Well absorbed from the gastrointestinal tract.
Lomper
side effects and Toxicity
Symptoms of overdose include coma, drowsiness, loss of muscle control, severely impaired breathing, shock, sluggishness, and unresponsiveness. Death has been reported with ingestion of as little as 12 g meprobamate and survival with as much as 40 g.
Lomper
Patient Information
Lomper
Organisms Affected
Humans and other mammals