Mebenoazole
Brand names,
Mebenoazole
Analogs
Mebenoazole
Brand Names Mixture
- Absorbine JR Antifungal Liquid (menthol + tolnaftate)
Mebenoazole
Chemical_Formula
C9H18N2O4
Mebenoazole
RX_link
http://www.rxlist.com/cgi/generic2/meprobamate.htm
Mebenoazole
fda sheet
Mebenoazole
msds (material safety sheet)
Mebenoazole
Synthesis Reference
No information avaliable
Mebenoazole
Molecular Weight
218.25 g/mol
Mebenoazole
Melting Point
105 oC
Mebenoazole
H2O Solubility
4700 mg/L
Mebenoazole
State
Solid
Mebenoazole
LogP
0.092
Mebenoazole
Dosage Forms
Tablet for oral administration (200 mg, 400 mg)
Mebenoazole
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety.
Mebenoazole
Pharmacology
Meprobamate is an anxiolytic drug. It was the best selling minor tranquilizer for a time but has largely been replaced by benzodiazepines. Meprobamate has most of the pharmacological effects and dangers of the barbiturates (though it was marketed as being safer). However, it is less sedating at effective doses. It is reported to have some anticonvulsant properties against absence seizures, but can exacerbate generalized tonic-clonic seizures. It has also been used as a hypnotic (sleeping pill). However, its is currently only licensed as an anxiolytic and it is a third or fourth-order choice.
Mebenoazole
Absorption
Well absorbed from the gastrointestinal tract.
Mebenoazole
side effects and Toxicity
Symptoms of overdose include coma, drowsiness, loss of muscle control, severely impaired breathing, shock, sluggishness, and unresponsiveness. Death has been reported with ingestion of as little as 12 g meprobamate and survival with as much as 40 g.
Mebenoazole
Patient Information
Mebenoazole
Organisms Affected
Humans and other mammals