Lutrefact
Lutrefact Brand names, Lutrefact Analogs
- Dirigestran
- Dirigestran Spofa
- Factrel
- Fertagyl
- Gonadorelina [INN-Spanish]
- Gonadorelinum [INN-Latin]
- Gonadotropin releasing hormone
- Gonadotropin-releasing factor
- Gonadotropin-releasing hormone
- Human LH-RH
- Hypocrine
- Luforan
- Lutal
- Lutamin
- Lutrefact
- Lutrepulse
- Lutrepulse KIT
- Mammalian GnRH
- Mammalian LH-RH
- Ovine LH-RH
- Porchine LH-RH
- Porcine LH-releasing factor
- Relefact
- Relisorm
- Relisorm L
- Synthetic Gn-RH
- Synthetic LH-FSH releasing hormone
- Synthetic LH-RF
- Synthetic LH-RH
- Synthetic LH-releasing factor
- Synthetic LH-releasing hormone
- Synthetic LRF
- Synthetic decapeptide FSH/LH-RH
- Synthetic gonadoliberin
Lutrefact Brand Names Mixture
- No information avaliable
Lutrefact Chemical_Formula
(FeO.OH.2H2O)478 (Dx.COOH)9
Lutrefact RX_link
http://www.rxlist.com/cgi/generic3/fedex.htm
Lutrefact fda sheet
Lutrefact msds (material safety sheet)
Lutrefact Synthesis Reference
No information avaliable
Lutrefact Molecular Weight
105000 g/mol (average)
Lutrefact Melting Point
No information avaliable
Lutrefact H2O Solubility
Soluble
Lutrefact State
Solid
Lutrefact LogP
No information avaliable
Lutrefact Dosage Forms
Solution (for intramuscular injection)
Lutrefact Indication
For treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. Also used to replenish body iron stores in Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD) patients receiving or not receiving erythropoietin and in Hemodialysis Dependent (HDD-CKD) and Peritoneal Dialysis Dependent (PDD-CKD) - Chronic Kidney Disease patients receiving an erythropoietin.
Lutrefact Pharmacology
Iron dextran is a dark brown, slightly viscous sterile liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. It is for treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. Iron is essential to the formation of hemoglobin and to the function and formation of other heme and nonheme compounds. Untreated depletion of iron stores leads to iron-deficient erythropoiesis and, in turn, to iron deficiency anemia.
Lutrefact Absorption
The major portion of intramuscular injections of iron dextran is absorbed within 72 hours; most of the remaining iron is absorbed over the ensuing 3 to 4 weeks.
Lutrefact side effects and Toxicity
LD50 = 500 mg/kg (mouse, IV). Dosages of iron dextran in excess of the requirements for restoration of hemoglobin and replenishment of iron stores may lead to hemosiderosis. Cases of severe, sometimes fatal, allergic reactions (loss of consciousness, collapse, difficulty breathing, hives, swelling, or convulsions) and severe low blood pressure (hypotension) have been reported with the use of iron dextran.
Lutrefact Patient Information
http://www.drugs.com/cons/Inulin.html
Lutrefact Organisms Affected
Humans and other mammals
