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Dirigestran Brand names, Dirigestran Analogs

Dirigestran Brand Names Mixture

  • No information avaliable

Dirigestran Chemical_Formula

(FeO.OH.2H2O)478 (Dx.COOH)9

Dirigestran RX_link

http://www.rxlist.com/cgi/generic3/fedex.htm

Dirigestran fda sheet

Dirigestran msds (material safety sheet)

Dirigestran MSDS

Dirigestran Synthesis Reference

No information avaliable

Dirigestran Molecular Weight

105000 g/mol (average)

Dirigestran Melting Point

No information avaliable

Dirigestran H2O Solubility

Soluble

Dirigestran State

Solid

Dirigestran LogP

No information avaliable

Dirigestran Dosage Forms

Solution (for intramuscular injection)

Dirigestran Indication

For treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. Also used to replenish body iron stores in Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD) patients receiving or not receiving erythropoietin and in Hemodialysis Dependent (HDD-CKD) and Peritoneal Dialysis Dependent (PDD-CKD) - Chronic Kidney Disease patients receiving an erythropoietin.

Dirigestran Pharmacology

Iron dextran is a dark brown, slightly viscous sterile liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. It is for treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. Iron is essential to the formation of hemoglobin and to the function and formation of other heme and nonheme compounds. Untreated depletion of iron stores leads to iron-deficient erythropoiesis and, in turn, to iron deficiency anemia.

Dirigestran Absorption

The major portion of intramuscular injections of iron dextran is absorbed within 72 hours; most of the remaining iron is absorbed over the ensuing 3 to 4 weeks.

Dirigestran side effects and Toxicity

LD50 = 500 mg/kg (mouse, IV). Dosages of iron dextran in excess of the requirements for restoration of hemoglobin and replenishment of iron stores may lead to hemosiderosis. Cases of severe, sometimes fatal, allergic reactions (loss of consciousness, collapse, difficulty breathing, hives, swelling, or convulsions) and severe low blood pressure (hypotension) have been reported with the use of iron dextran.

Dirigestran Patient Information

http://www.drugs.com/cons/Inulin.html

Dirigestran Organisms Affected

Humans and other mammals