Dirigestran
Dirigestran Brand names, Dirigestran Analogs
- Dirigestran
- Dirigestran Spofa
- Factrel
- Fertagyl
- Gonadorelina [INN-Spanish]
- Gonadorelinum [INN-Latin]
- Gonadotropin releasing hormone
- Gonadotropin-releasing factor
- Gonadotropin-releasing hormone
- Human LH-RH
- Hypocrine
- Luforan
- Lutal
- Lutamin
- Lutrefact
- Lutrepulse
- Lutrepulse KIT
- Mammalian GnRH
- Mammalian LH-RH
- Ovine LH-RH
- Porchine LH-RH
- Porcine LH-releasing factor
- Relefact
- Relisorm
- Relisorm L
- Synthetic Gn-RH
- Synthetic LH-FSH releasing hormone
- Synthetic LH-RF
- Synthetic LH-RH
- Synthetic LH-releasing factor
- Synthetic LH-releasing hormone
- Synthetic LRF
- Synthetic decapeptide FSH/LH-RH
- Synthetic gonadoliberin
Dirigestran Brand Names Mixture
- No information avaliable
Dirigestran Chemical_Formula
(FeO.OH.2H2O)478 (Dx.COOH)9
Dirigestran RX_link
http://www.rxlist.com/cgi/generic3/fedex.htm
Dirigestran fda sheet
Dirigestran msds (material safety sheet)
Dirigestran Synthesis Reference
No information avaliable
Dirigestran Molecular Weight
105000 g/mol (average)
Dirigestran Melting Point
No information avaliable
Dirigestran H2O Solubility
Soluble
Dirigestran State
Solid
Dirigestran LogP
No information avaliable
Dirigestran Dosage Forms
Solution (for intramuscular injection)
Dirigestran Indication
For treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. Also used to replenish body iron stores in Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD) patients receiving or not receiving erythropoietin and in Hemodialysis Dependent (HDD-CKD) and Peritoneal Dialysis Dependent (PDD-CKD) - Chronic Kidney Disease patients receiving an erythropoietin.
Dirigestran Pharmacology
Iron dextran is a dark brown, slightly viscous sterile liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. It is for treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. Iron is essential to the formation of hemoglobin and to the function and formation of other heme and nonheme compounds. Untreated depletion of iron stores leads to iron-deficient erythropoiesis and, in turn, to iron deficiency anemia.
Dirigestran Absorption
The major portion of intramuscular injections of iron dextran is absorbed within 72 hours; most of the remaining iron is absorbed over the ensuing 3 to 4 weeks.
Dirigestran side effects and Toxicity
LD50 = 500 mg/kg (mouse, IV). Dosages of iron dextran in excess of the requirements for restoration of hemoglobin and replenishment of iron stores may lead to hemosiderosis. Cases of severe, sometimes fatal, allergic reactions (loss of consciousness, collapse, difficulty breathing, hives, swelling, or convulsions) and severe low blood pressure (hypotension) have been reported with the use of iron dextran.
Dirigestran Patient Information
http://www.drugs.com/cons/Inulin.html
Dirigestran Organisms Affected
Humans and other mammals
