Imidourea en es it fr

Imidourea Brand names, Imidourea Analogs

Imidourea Brand Names Mixture

  • No information avaliable

Imidourea Chemical_Formula


Imidourea RX_link

No information avaliable

Imidourea fda sheet

Imidourea msds (material safety sheet)

Imidourea MSDS

Imidourea Synthesis Reference

No information avaliable

Imidourea Molecular Weight

59.0706 g/mol

Imidourea Melting Point

183 oC (HCl salt)

Imidourea H2O Solubility

500 mg/mL (HCl salt)

Imidourea State


Imidourea LogP


Imidourea Dosage Forms

No information avaliable

Imidourea Indication

For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indicated for treating myasthenia gravis.

Imidourea Pharmacology

Guanidine apparently acts by enhancing the release of acetylcholine following a nerve impulse. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes.

Imidourea Absorption

Rapidly absorbed and distributed

Imidourea side effects and Toxicity

LD50 = 475 mg/kg (oral, rat). Can cause severe gastrointestinal symptoms (nausea, vomiting and diarrhea), bone marrow suppression, renal insufficiency and other hematologic abnormalities (anemia, leucopenia). Severe guanidine intoxication is characterized by nervous hyperirritability, fibrillary tremors and convulsive contractions of muscle, salivation, vomiting, diarrhea, hypoglycemia, and circulatory disturbances.

Imidourea Patient Information

No information avaliable

Imidourea Organisms Affected

Humans and other mammals