Guanidinium Sulfate
Guanidinium Sulfate Brand names, Guanidinium Sulfate Analogs
Guanidinium Sulfate Brand Names Mixture
- No information avaliable
Guanidinium Sulfate Chemical_Formula
CH5N3
Guanidinium Sulfate RX_link
No information avaliable
Guanidinium Sulfate fda sheet
Guanidinium Sulfate msds (material safety sheet)
Guanidinium Sulfate Synthesis Reference
No information avaliable
Guanidinium Sulfate Molecular Weight
59.0706 g/mol
Guanidinium Sulfate Melting Point
183 oC (HCl salt)
Guanidinium Sulfate H2O Solubility
500 mg/mL (HCl salt)
Guanidinium Sulfate State
Solid
Guanidinium Sulfate LogP
-0.946
Guanidinium Sulfate Dosage Forms
No information avaliable
Guanidinium Sulfate Indication
For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indicated for treating myasthenia gravis.
Guanidinium Sulfate Pharmacology
Guanidine apparently acts by enhancing the release of acetylcholine following a nerve impulse. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes.
Guanidinium Sulfate Absorption
Rapidly absorbed and distributed
Guanidinium Sulfate side effects and Toxicity
LD50 = 475 mg/kg (oral, rat). Can cause severe gastrointestinal symptoms (nausea, vomiting and diarrhea), bone marrow suppression, renal insufficiency and other hematologic abnormalities (anemia, leucopenia). Severe guanidine intoxication is characterized by nervous hyperirritability, fibrillary tremors and convulsive contractions of muscle, salivation, vomiting, diarrhea, hypoglycemia, and circulatory disturbances.
Guanidinium Sulfate Patient Information
No information avaliable
Guanidinium Sulfate Organisms Affected
Humans and other mammals
