Aminomethanamidine en es it fr

Aminomethanamidine Brand names, Aminomethanamidine Analogs

Aminomethanamidine Brand Names Mixture

  • No information avaliable

Aminomethanamidine Chemical_Formula


Aminomethanamidine RX_link

No information avaliable

Aminomethanamidine fda sheet

Aminomethanamidine msds (material safety sheet)

Aminomethanamidine MSDS

Aminomethanamidine Synthesis Reference

No information avaliable

Aminomethanamidine Molecular Weight

59.0706 g/mol

Aminomethanamidine Melting Point

183 oC (HCl salt)

Aminomethanamidine H2O Solubility

500 mg/mL (HCl salt)

Aminomethanamidine State


Aminomethanamidine LogP


Aminomethanamidine Dosage Forms

No information avaliable

Aminomethanamidine Indication

For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indicated for treating myasthenia gravis.

Aminomethanamidine Pharmacology

Guanidine apparently acts by enhancing the release of acetylcholine following a nerve impulse. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes.

Aminomethanamidine Absorption

Rapidly absorbed and distributed

Aminomethanamidine side effects and Toxicity

LD50 = 475 mg/kg (oral, rat). Can cause severe gastrointestinal symptoms (nausea, vomiting and diarrhea), bone marrow suppression, renal insufficiency and other hematologic abnormalities (anemia, leucopenia). Severe guanidine intoxication is characterized by nervous hyperirritability, fibrillary tremors and convulsive contractions of muscle, salivation, vomiting, diarrhea, hypoglycemia, and circulatory disturbances.

Aminomethanamidine Patient Information

No information avaliable

Aminomethanamidine Organisms Affected

Humans and other mammals