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Carbamidine Brand names, Carbamidine Analogs

Carbamidine Brand Names Mixture

  • No information avaliable

Carbamidine Chemical_Formula


Carbamidine RX_link

No information avaliable

Carbamidine fda sheet

Carbamidine msds (material safety sheet)

Carbamidine MSDS

Carbamidine Synthesis Reference

No information avaliable

Carbamidine Molecular Weight

59.0706 g/mol

Carbamidine Melting Point

183 oC (HCl salt)

Carbamidine H2O Solubility

500 mg/mL (HCl salt)

Carbamidine State


Carbamidine LogP


Carbamidine Dosage Forms

No information avaliable

Carbamidine Indication

For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indicated for treating myasthenia gravis.

Carbamidine Pharmacology

Guanidine apparently acts by enhancing the release of acetylcholine following a nerve impulse. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes.

Carbamidine Absorption

Rapidly absorbed and distributed

Carbamidine side effects and Toxicity

LD50 = 475 mg/kg (oral, rat). Can cause severe gastrointestinal symptoms (nausea, vomiting and diarrhea), bone marrow suppression, renal insufficiency and other hematologic abnormalities (anemia, leucopenia). Severe guanidine intoxication is characterized by nervous hyperirritability, fibrillary tremors and convulsive contractions of muscle, salivation, vomiting, diarrhea, hypoglycemia, and circulatory disturbances.

Carbamidine Patient Information

No information avaliable

Carbamidine Organisms Affected

Humans and other mammals