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Guanidin Brand names, Guanidin Analogs

Guanidin Brand Names Mixture

  • No information avaliable

Guanidin Chemical_Formula


Guanidin RX_link

No information avaliable

Guanidin fda sheet

Guanidin msds (material safety sheet)

Guanidin MSDS

Guanidin Synthesis Reference

No information avaliable

Guanidin Molecular Weight

59.0706 g/mol

Guanidin Melting Point

183 oC (HCl salt)

Guanidin H2O Solubility

500 mg/mL (HCl salt)

Guanidin State


Guanidin LogP


Guanidin Dosage Forms

No information avaliable

Guanidin Indication

For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indicated for treating myasthenia gravis.

Guanidin Pharmacology

Guanidine apparently acts by enhancing the release of acetylcholine following a nerve impulse. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes.

Guanidin Absorption

Rapidly absorbed and distributed

Guanidin side effects and Toxicity

LD50 = 475 mg/kg (oral, rat). Can cause severe gastrointestinal symptoms (nausea, vomiting and diarrhea), bone marrow suppression, renal insufficiency and other hematologic abnormalities (anemia, leucopenia). Severe guanidine intoxication is characterized by nervous hyperirritability, fibrillary tremors and convulsive contractions of muscle, salivation, vomiting, diarrhea, hypoglycemia, and circulatory disturbances.

Guanidin Patient Information

No information avaliable

Guanidin Organisms Affected

Humans and other mammals