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Carbamamidine Brand names, Carbamamidine Analogs

Carbamamidine Brand Names Mixture

  • No information avaliable

Carbamamidine Chemical_Formula


Carbamamidine RX_link

No information avaliable

Carbamamidine fda sheet

Carbamamidine msds (material safety sheet)

Carbamamidine MSDS

Carbamamidine Synthesis Reference

No information avaliable

Carbamamidine Molecular Weight

59.0706 g/mol

Carbamamidine Melting Point

183 oC (HCl salt)

Carbamamidine H2O Solubility

500 mg/mL (HCl salt)

Carbamamidine State


Carbamamidine LogP


Carbamamidine Dosage Forms

No information avaliable

Carbamamidine Indication

For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indicated for treating myasthenia gravis.

Carbamamidine Pharmacology

Guanidine apparently acts by enhancing the release of acetylcholine following a nerve impulse. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes.

Carbamamidine Absorption

Rapidly absorbed and distributed

Carbamamidine side effects and Toxicity

LD50 = 475 mg/kg (oral, rat). Can cause severe gastrointestinal symptoms (nausea, vomiting and diarrhea), bone marrow suppression, renal insufficiency and other hematologic abnormalities (anemia, leucopenia). Severe guanidine intoxication is characterized by nervous hyperirritability, fibrillary tremors and convulsive contractions of muscle, salivation, vomiting, diarrhea, hypoglycemia, and circulatory disturbances.

Carbamamidine Patient Information

No information avaliable

Carbamamidine Organisms Affected

Humans and other mammals