Guanidinium Chloride en es it fr

Guanidinium Chloride Brand names, Guanidinium Chloride Analogs

Guanidinium Chloride Brand Names Mixture

  • No information avaliable

Guanidinium Chloride Chemical_Formula

CH5N3

Guanidinium Chloride RX_link

No information avaliable

Guanidinium Chloride fda sheet

Guanidinium Chloride msds (material safety sheet)

Guanidinium_Chloride MSDS

Guanidinium Chloride Synthesis Reference

No information avaliable

Guanidinium Chloride Molecular Weight

59.0706 g/mol

Guanidinium Chloride Melting Point

183 oC (HCl salt)

Guanidinium Chloride H2O Solubility

500 mg/mL (HCl salt)

Guanidinium Chloride State

Solid

Guanidinium Chloride LogP

-0.946

Guanidinium Chloride Dosage Forms

No information avaliable

Guanidinium Chloride Indication

For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indicated for treating myasthenia gravis.

Guanidinium Chloride Pharmacology

Guanidine apparently acts by enhancing the release of acetylcholine following a nerve impulse. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes.

Guanidinium Chloride Absorption

Rapidly absorbed and distributed

Guanidinium Chloride side effects and Toxicity

LD50 = 475 mg/kg (oral, rat). Can cause severe gastrointestinal symptoms (nausea, vomiting and diarrhea), bone marrow suppression, renal insufficiency and other hematologic abnormalities (anemia, leucopenia). Severe guanidine intoxication is characterized by nervous hyperirritability, fibrillary tremors and convulsive contractions of muscle, salivation, vomiting, diarrhea, hypoglycemia, and circulatory disturbances.

Guanidinium Chloride Patient Information

No information avaliable

Guanidinium Chloride Organisms Affected

Humans and other mammals