Guanidinium Chloride
Guanidinium Chloride Brand names, Guanidinium Chloride Analogs
Guanidinium Chloride Brand Names Mixture
- No information avaliable
Guanidinium Chloride Chemical_Formula
CH5N3
Guanidinium Chloride RX_link
No information avaliable
Guanidinium Chloride fda sheet
Guanidinium Chloride msds (material safety sheet)
Guanidinium Chloride Synthesis Reference
No information avaliable
Guanidinium Chloride Molecular Weight
59.0706 g/mol
Guanidinium Chloride Melting Point
183 oC (HCl salt)
Guanidinium Chloride H2O Solubility
500 mg/mL (HCl salt)
Guanidinium Chloride State
Solid
Guanidinium Chloride LogP
-0.946
Guanidinium Chloride Dosage Forms
No information avaliable
Guanidinium Chloride Indication
For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indicated for treating myasthenia gravis.
Guanidinium Chloride Pharmacology
Guanidine apparently acts by enhancing the release of acetylcholine following a nerve impulse. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes.
Guanidinium Chloride Absorption
Rapidly absorbed and distributed
Guanidinium Chloride side effects and Toxicity
LD50 = 475 mg/kg (oral, rat). Can cause severe gastrointestinal symptoms (nausea, vomiting and diarrhea), bone marrow suppression, renal insufficiency and other hematologic abnormalities (anemia, leucopenia). Severe guanidine intoxication is characterized by nervous hyperirritability, fibrillary tremors and convulsive contractions of muscle, salivation, vomiting, diarrhea, hypoglycemia, and circulatory disturbances.
Guanidinium Chloride Patient Information
No information avaliable
Guanidinium Chloride Organisms Affected
Humans and other mammals
