Hydromorphone HCL en es it fr

Hydromorphone HCL Brand names, Hydromorphone HCL Analogs

Hydromorphone HCL Brand Names Mixture

  • No information avaliable

Hydromorphone HCL Chemical_Formula


Hydromorphone HCL RX_link


Hydromorphone HCL fda sheet

Hydromorphone_HCL FDA

Hydromorphone HCL msds (material safety sheet)

Hydromorphone_HCL MSDS

Hydromorphone HCL Synthesis Reference

No information avaliable

Hydromorphone HCL Molecular Weight

285.338 g/mol

Hydromorphone HCL Melting Point

266-267 oC

Hydromorphone HCL H2O Solubility

No information avaliable

Hydromorphone HCL State


Hydromorphone HCL LogP

1.28 (Roy, SD; Flynn, GL Pharm. Res. 5:580 (1988))

Hydromorphone HCL Dosage Forms

Capsule (controlled-delivery); Solution; Tablet

Hydromorphone HCL Indication

For the relief of moderate to severe pain such as that due to surgery, cancer, trauma/injury, burns, myocardial infarction and colic.

Hydromorphone HCL Pharmacology

Hydromorphone is a hydrogenated ketone derivative of morphine that acts as a narcotic analgesic. It has a shorter duration of action than morphine. Hydromorphone is approximately 8 times more potent on a milligram basis than morphine. In addition, hydromorphone is better absorbed orally than is morphine. In clinical settings, Hydromorphone exerts its principal pharmacological effect on the central nervous system and gastrointestinal tract. Its primary actions of therapeutic value are analgesia and sedation. Hydromorphone appears to increase the patient's tolerance for pain and to decrease discomfort, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Opioids also produce respiratory depression by direct action on brain stem respiratory centers.

Hydromorphone HCL Absorption

Better absorbed orally than morphine

Hydromorphone HCL side effects and Toxicity

Hydromorphone is a schedule II narcotic which can lead to physical dependence or addiction. High doses lead to respiratory depression, nausea, and vomiting. Overdoses lead to extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, and sometimes bradycardia and hypotension. In severe overdosage, apnea, circulatory collapse, cardiac arrest and death may occur.

Hydromorphone HCL Patient Information


Hydromorphone HCL Organisms Affected

Humans and other mammals