Dihydromorphinone en es it fr

Dihydromorphinone Brand names, Dihydromorphinone Analogs

Dihydromorphinone Brand Names Mixture

  • No information avaliable

Dihydromorphinone Chemical_Formula


Dihydromorphinone RX_link


Dihydromorphinone fda sheet

Dihydromorphinone FDA

Dihydromorphinone msds (material safety sheet)

Dihydromorphinone MSDS

Dihydromorphinone Synthesis Reference

No information avaliable

Dihydromorphinone Molecular Weight

285.338 g/mol

Dihydromorphinone Melting Point

266-267 oC

Dihydromorphinone H2O Solubility

No information avaliable

Dihydromorphinone State


Dihydromorphinone LogP

1.28 (Roy, SD; Flynn, GL Pharm. Res. 5:580 (1988))

Dihydromorphinone Dosage Forms

Capsule (controlled-delivery); Solution; Tablet

Dihydromorphinone Indication

For the relief of moderate to severe pain such as that due to surgery, cancer, trauma/injury, burns, myocardial infarction and colic.

Dihydromorphinone Pharmacology

Hydromorphone is a hydrogenated ketone derivative of morphine that acts as a narcotic analgesic. It has a shorter duration of action than morphine. Hydromorphone is approximately 8 times more potent on a milligram basis than morphine. In addition, hydromorphone is better absorbed orally than is morphine. In clinical settings, Hydromorphone exerts its principal pharmacological effect on the central nervous system and gastrointestinal tract. Its primary actions of therapeutic value are analgesia and sedation. Hydromorphone appears to increase the patient's tolerance for pain and to decrease discomfort, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Opioids also produce respiratory depression by direct action on brain stem respiratory centers.

Dihydromorphinone Absorption

Better absorbed orally than morphine

Dihydromorphinone side effects and Toxicity

Hydromorphone is a schedule II narcotic which can lead to physical dependence or addiction. High doses lead to respiratory depression, nausea, and vomiting. Overdoses lead to extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, and sometimes bradycardia and hypotension. In severe overdosage, apnea, circulatory collapse, cardiac arrest and death may occur.

Dihydromorphinone Patient Information


Dihydromorphinone Organisms Affected

Humans and other mammals